Recent publications
Article
Cartography Consortium, Liu, F, Shi, H, Turner, JD, Anscombe, R, Li, J, Sekine, T, Hammitzsch, A, Agarwal, D, Mahony, C, Chen, J, Kendrick, B, Du, D, Tong, Q, Duan, L, Dooley, K, Fang, H, Korsunsky, I, Madhu, R, Cribbs, AP, Friedrich, M, Marsden, BD, Chen, Y-L, Ogg, G, Adams, A, Chen, W, Leonardo, S, McCann, FE, Buckley, CD, Rooney, T, Freeman, T, Uhlig, HH, Dendrou, C, Croft, A, Filer, A, Bowness, P & Chen, L 2025, 'CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue', Annals of the Rheumatic Diseases, vol. 84, no. 7, pp. 1151-1163. https://doi.org/10.1016/j.ard.2025.04.018
Roche Fibroblast Network Consortium 2025, 'Molecular and spatial analysis of tertiary lymphoid structures in Sjogren's syndrome', Nature Communications, vol. 16, no. 1, 5. https://doi.org/10.1038/s41467-024-54686-0
Bolton, C, Mahony, CB, Clay, E, Reis Nisa, P, Lomholt, S, Hackland, A, Chin, PS, Smith, CG, Alexiou, V, Nguyen, HD, Thyagarajan, M, Sheikh, Z, Davis, P, Chippington, S, Compeyrot-Lacassagne, S, Davda, S, Foley, C, Turtsevich, I, Ingledow, B, Kupiec, K, Kelly, J, Hanlon, MM, DiCarlo, E, Jones, LJ, Smith, SL, Eyre, S, Neag, G, Kemble, S, Madhu, R, Palshikar, MG, Korsunsky, I, Gao, C, Tran, M, Dendrou, C, Buckley, CD, Coles, MC, Raza, K, MAPJAG Study Group, Gravallese, E, Filer, A, Wei, K, Al-Abadi, E, Rosser, EC, Wedderburn, LR & Croft, A 2025, 'Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity', Science Translational Medicine, vol. 17, no. 805, eadt6050. https://doi.org/10.1126/scitranslmed.adt6050
Rauber, S, Mohammadian, H, Schmidkonz, C, Atzinger, A, Soare, A, Treutlein, C, Kemble, S, Mahony, CB, Geisthoff, M, Angeli, MR, Raimondo, MG, Xu, C, Yang, K-T, Lu, L, Labinsky, H, Saad, MSA, Gwellem, CA, Chang, J, Huang, K, Kampylafka, E, Knitza, J, Bilyy, R, Distler, JHW, Hanlon, MM, Fearon, U, Veale, DJ, Roemer, FW, Bäuerle, T, Maric, HM, Maschauer, S, Ekici, AB, Buckley, CD, Croft, AP, Kuwert, T, Prante, O, Cañete, JD, Schett, G & Ramming, A 2024, 'CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis', Nature Immunology. https://doi.org/10.1038/s41590-024-01774-4
Baruah, P, Marshall, JL, Nefla, M, Pucino, V, Adams, H, Turner, JD, Gilbert, S, Powell, E, Neag, G, Monksfield, P, Irving, RM, Croft, AP, Dumitriu, IE & Buckley, CD 2024, 'Functional analysis of fibroblasts and macrophages in head and neck paragangliomas', Frontiers in Endocrinology, vol. 15, 1397839. https://doi.org/10.3389/fendo.2024.1397839
Coyle, C, Ma, M, Abraham, Y, Mahony, CB, Steel, K, Simpson, C, Guerra, N, Croft, AP, Rapecki, S, Cope, A, Bowcutt, R & Perucha, E 2024, 'NK cell subsets define sustained remission in rheumatoid arthritis', JCI Insight, vol. 9, no. 23, e182390. https://doi.org/10.1172/jci.insight.182390
Baruah, P, Mahony, C, Marshall, JL, Smith, CG, Monksfield, P, Irving, RI, Dumitriu, IE, Buckley, CD & Croft, AP 2024, 'Single-cell RNA sequencing analysis of vestibular schwannoma reveals functionally distinct macrophage subsets', British Journal of Cancer, vol. 130, no. 10, pp. 1659-1669. https://doi.org/10.1038/s41416-024-02646-2
Murillo-Saich, JD, Coras, R, Ramirez, J, Quesada-Masachs, E, Sala-Climent, M, Eschelbach, K, Mahony, CB, Celis, R, Armando, A, Quehenberger, O, Croft, AP, Kavanaugh, A, Chang, E, Cañete, JD, Singh, A & Guma, M 2024, 'Synovial 5-LOX-derived oxylipins define a lympho-myeloid-enriched synovium', Arthritis & Rheumatology (Hoboken), vol. 76, no. 8, pp. 1230-1242. https://doi.org/10.1002/art.42848
Ahmed, S, Mahony, CB, Torres, A, Murillo-Saich, J, Kemble, S, Cedeno, M, John, P, Bhatti, A, Croft, AP & Guma, M 2023, 'Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis', Arthritis Research & Therapy, vol. 25, no. 1, 176. https://doi.org/10.1186/s13075-023-03161-0
Khan, AO, Rodriguez-Romera, A, Reyat, JS, Olijnik, AA, Colombo, M, Wang, G, Wen, WX, Sousos, N, Murphy, LC, Grygielska, B, Perrella, G, Mahony, CB, Ling, RE, Elliott, NE, Karali, CS, Stone, AP, Kemble, S, Cutler, EA, Fielding, AK, Croft, AP, Bassett, D, Poologasundarampillai, G, Roy, A, Gooding, S, Rayes, J, Machlus, KR & Psaila, B 2023, 'Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies', Cancer Discovery, vol. 13, no. 2, pp. 364-385. https://doi.org/10.1158/2159-8290.CD-22-0199
Comment/debate
Bolton, C & Croft, AP 2024, 'All fibroblasts are equal, but some are more equal than others', Nature Reviews Rheumatology. https://doi.org/10.1038/s41584-024-01097-6
Hackland, A & Croft, AP 2023, 'Are the origins of adult arthritis seeded during embryonic development?', Nature Reviews Rheumatology, vol. 19, no. 3, pp. 132-133. https://doi.org/10.1038/s41584-023-00911-x
Preprint
Accelerating Medicines Partnership RA/SLE Network 2025 'Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis' bioRxiv. https://doi.org/10.1101/2025.03.14.642821
Mueller, AA, Zou, AE, Marsh, L-J, Kemble, S, Nayar, S, Watts, GFM, Murphy, CL, Taylor, E, Major, T, Gardner, D, Buckley, CD, Wei, K, Raychaudhuri, S, Korsunsky, I, Filer, A, Croft, AP & Brenner, MB 2025 'Wnt signaling drives stromal inflammation in inflammatory arthritis' bioRxiv. https://doi.org/10.1101/2025.01.06.631510
Review article
Karsdal, M, Cox, TR, Parker, AL, Willumsen, N, Sand, JMB, Jenkins, G, Hansen, HH, Oldenburger, A, Geillinger-Kaestle, KE, Larsen, AT, Black, D, Genovese, F, Eckersley, A, Heinz, A, Nyström, A, Holm Nielsen, S, Bennink, L, Johannsson, L, Bay-Jensen, A-C, Orange, DE, Friedman, S, Røpke, M, Fiore, V, Schuppan, D, Rieder, F, Simona, B, Borthwick, L, Skarsfeldt, M, Wennbo, H, Thakker, P, Stoffel, R, Clarke, GW, Kalluri, R, Ruane, D, Zannad, F, Mortensen, JH, Sinkeviciute, D, Sundberg, F, Coseno, M, Thudium, C, Croft, AP, Khanna, D, Cooreman, M, Broermann, A, Leeming, DJ, Mobasheri, A & Ricard-Blum, S 2025, 'Advances in Extracellular Matrix-Associated Diagnostics and Therapeutics', Journal of Clinical Medicine, vol. 14, no. 6, 1856. https://doi.org/10.3390/jcm14061856
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