Recent publications
Article
Roy, A, O'Shea, C, Dasí, A, Patel, L, Cumberland, MJ, Nieves, D, Canagarajah, H, Thompson, S, Azad, A, Price, A, Hall, C, Alvior, AM, Rath, P, Davies, B, Rodriguez, B, Holmes, AP, Pavlovic, D, Townend, JN, Geberhiwot, T, Gehmlich, K & Steeds, RP 2025, 'Early Atrial Remodeling Drives Arrhythmia in Fabry Disease', Circulation Arrhythmia and Electrophysiology. https://doi.org/10.1161/CIRCEP.124.013352
Roy, A, Cumberland, M, O'Shea, C, Holmes, A, Kalla, M, Gehmlich, K, Geberhiwot, T & Steeds, R 2024, 'Arrhythmogenesis in Fabry Disease', Current cardiology reports. https://doi.org/10.1007/s11886-024-02053-2
Cumberland, M, Euchner, J, Azad, A, Vo, NTN, Kirchhof, P, Holmes, A, Denning, C & Gehmlich, K 2024, 'Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue model [version 1; peer review: 1 approved, 2 approved with reservations]', F1000Research, vol. 12, 1224. https://doi.org/10.12688/f1000research.139482.1
Sommerfeld, LC, Holmes, AP, Yu, TY, O'Shea, C, Kavanagh, DM, Pike, JM, Wright, T, Syeda, F, Aljehani, A, Kew, T, Cardoso, VR, Kabir, SN, Hepburn, C, Menon, PR, Broadway‐Stringer, S, O'Reilly, M, Witten, A, Fortmueller, L, Lutz, S, Kulle, A, Gkoutos, GV, Pavlovic, D, Arlt, W, Lavery, GG, Steeds, R, Gehmlich, K, Stoll, M, Kirchhof, P & Fabritz, L 2024, 'Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse', The Journal of Physiology. https://doi.org/10.1113/jp284597
Holmes, AP & Kumar, P 2023, 'Low sugar and the drive to breathe: Is insulin another adequate stimulus for the carotid body?', Experimental Physiology, vol. 108, no. 2, pp. 167-168. https://doi.org/10.1113/EP091008
Cumberland, M, Riebel, LL, Roy, A, O'Shea, C, Holmes, A, Denning, C, Kirchhof, P, Rodriguez, B & Gehmlich, K 2022, 'Basic Research Approaches to Evaluate Cardiac Arrhythmia in Heart Failure and Beyond', Frontiers in Physiology, vol. 13, 806366. https://doi.org/10.3389/fphys.2022.806366
Al-Maswary, AA, O'Reilly, M, Holmes, AP, Walmsley, AD, Cooper, PR & Scheven, BA 2022, 'Exploring the neurogenic differentiation of human dental pulp stem cells', PLoS ONE, vol. 17, no. 11, e0277134. https://doi.org/10.1371/journal.pone.0277134
O'Reilly, M, Sommerfeld, LC, O'Shea, C, Broadway-Stringer, S, Andaleeb, S, Reyat, JS, Kabir, SN, Stastny, D, Malinova, A, Delbue, D, Fortmueller, L, Gehmlich, K, Pavlovic, D, Skryabin, BV, Holmes, AP, Kirchhof, P & Fabritz, L 2022, 'Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide', EP Europace. https://doi.org/10.1093/europace/euac218
O’Shea, C, Winter, J, Kabir, SN, O’Reilly, M, Wells, SP, Baines, O, Sommerfeld, LC, Correia, J, Lei, M, Kirchhof, P, Holmes, AP, Fabritz, L, Rajpoot, K & Pavlovic, D 2022, 'High resolution optical mapping of cardiac electrophysiology in pre-clinical models', Scientific Data, vol. 9, no. 1, 135. https://doi.org/10.1038/s41597-022-01253-1
Abstract
Briggs, D, Hunt, J, Raut, S, Saleeb-Mousa, J, Coney, A, Kalla, M, Holmes, A & Brain, K 2024, 'High-resolution ex-vivo structural and functional analysis of sympathetic innervation using a novel confocal fluorescence technique', Congress of The International Society for Autonomic Neuroscience, Birmingham, United Kingdom, 25/07/24 - 27/07/24 pp. 177-177. <https://airdrive.eventsair.com/eventsairwesteuprod/production-uobevents-public/88221d9f811643979a2503a63fee9877>
Conference contribution
Aldossary, HS, Nieves, DJ, Kavanagh, DM, Owen, D, Ray, CJ, Kumar, P, Coney, AM & Holmes, AP 2023, Analyzing Angiotensin II Receptor Type 1 Clustering in PC12 Cells in Response to Hypoxia Using Direct Stochastic Optical Reconstruction Microscopy (dSTORM). in SV Conde, R Iturriaga, R del Rio, E Gauda & EC Monteiro (eds), Arterial Chemoreceptors: Mal(adaptive) Responses: O2 Dependent and Independent Mechanisms. 1 edn, Advances in Experimental Medicine and Biology, vol. 1427, Springer, pp. 175-184, ISAC XXI 2022, Lisbon, Portugal, 27/06/22. https://doi.org/10.1007/978-3-031-32371-3_19
Review article
Sha, R, Baines, O, Hayes, A, Tompkins, K, Kalla, M, Holmes, AP, O'Shea, C & Pavlovic, D 2024, 'Impact of Obesity on Atrial Fibrillation Pathogenesis and Treatment Options', Journal of the American Heart Association, vol. 13, no. 1, e032277. https://doi.org/10.1161/JAHA.123.032277
Baines, O, Sha, R, Kalla, M, Holmes, AP, Efimov, IR, Pavlovic, D & O’Shea, C 2024, 'Optical mapping and optogenetics in cardiac electrophysiology research and therapy: a state-of-the-art review', Europace, vol. 26, no. 2, euae017, pp. 1-14. https://doi.org/10.1093/europace/euae017
Saleeb-Mousa, J, Nathanael, D, Coney, AM, Kalla, M, Brain, KL & Holmes, AP 2023, 'Mechanisms of Atrial Fibrillation in Obstructive Sleep Apnoea', Cells, vol. 12, no. 12, 1661. https://doi.org/10.3390/cells12121661
Holmes, AP, Swiderska, A, Nathanael, D, Aldossary, HS, Ray, CJ, Coney, AM & Kumar, P 2022, 'Are multiple mitochondrial related signalling pathways involved in carotid body oxygen sensing?', Frontiers in Physiology, vol. 13, 908617. https://doi.org/10.3389/fphys.2022.908617
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